My American Pie-esque experience with "hot peppers":
I had made pico de gallo earlier in the day, which requires cutting up fresh jalepeños.
Later in the evening I was partying with my girlfriend and making Cube Librés, which requires cutting up fresh limes.
I thought I had washed the cutting board well.
Soon our tingling, engorged naughty bits soon became BURNING, engorged naughty bits.
Quoth the girlfriend: "My hoo-hoos on fire".
Funny as hell, though I only laughed when I was out of earshot while retrieving coolant for said BURNING, engorged naughty bits.